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Saturday, April 18, 2020

A Sense of Doubt blog post #1887 - What Our Leaders Can Do Now - By Bill Gates



A Sense of Doubt blog post #1887 - What Our Leaders Can Do Now - By Bill Gates

STATE OF THE PANDEMIC - TODAY
(a bit off in time)

COVID-19 Dashboard by the Center for Systems Science and Engineering (CSSE) at Johns Hopkins University (JHU)




Like many of us, I have had a love-hate relationship with Bill Gates, though maybe it's more accurate to say with Microsoft and Windows. Most of the "hate" (and not really hate but dislike, anger, frustration, caution, disgust) were feelings evoked by Microsoft's  near monopoly on the PC industry via Windows and its products and how Microsoft conducted its business, despite having Brian Eno pen the Windows 95 start up music. You know, because I am such a huge fan.

https://theindustryobserver.thebrag.com/the-odd-story-of-how-brian-eno-composed-the-windows-95-startup-sound/



Having Eno involved did help my relationship with Microsoft and Windows. I have never been a rabid Mac person, and I am only a recent Linux maven, and so I suffered through Windows 98 and Windows XP as the operating system seemed like a necessary evil. And then it started to become less evil. Windows 7 was very good, and so far Windows 10 is excellent. Smarter decisions have been made.

It seems that Bill Gates public image and perception in relation to the company has changed also, though this is clearly just my subjective assessment of him and his image. Seeing comments posted with his article reveal that many still harbor a great deal of resentment and bitterness if not outright rage for Bill Gates. I am not going to reprint any of that idiocy, but if you follow the link, you can find it for yourself mixed among some actual cogent and reasonable comments.

And yet, Bill Gates has been a much needed intelligent, forthright, and sagacious voice of reason in this new world of pandemic survival and response.

Gates was looked to for his reactions and no small amount of expertise as a kind of "told you so" after he delivered a Ted Talk in 2015 about epidemics, namely Ebola, and how a big one was surely coming and we (the world but certainly the United States) were not prepared. See the video and the transcript after the more recent Ted talk and Gates' blog reprinted below.

Recently, in the time of the shut down due to the pandemic, Gates has been looked to for guidance and to reprise his 2015 commentary. About the same time as publishing the blog entry that I reprint here, he gave a special Ted Talk on the current situation, which I will include below.




Gates speaks carefully. He avoids any really strong condemnation of the response by the federal government and instead passionately but gently urges for what must be done in testing, financial support, and vaccination while also putting his money where his mouth is in donations and assistance through his foundation.

I take back every negative thing I have ever said about this wonderful and kind soul.

I have no problem admitting when I am wrong. :-)

Thank you Bill Gates. Your voice is needed now more than ever.

Here's the rest:

Link to article's home on the Internet is in the title below.

i18n_series_logo

Gates Notes The blog of Bill Gates 

What our leaders can do now

There’s no question the United States missed the opportunity to get ahead of the novel coronavirus. But the window for making important decisions hasn’t closed. The choices we and our leaders make now will have an enormous impact on how soon case numbers start to go down, how long the economy remains shut down and how many Americans will have to bury a loved one because of COVID-19.
Our foundation has been working to slow the outbreak for several months. To date, we’ve invested $105 million in efforts to create new therapeutics, expand access to testing, and limit the virus’s impact here in Seattle.Coronavirus (COVID-19) Information and Updates | The University of ...
As a result of this work, I’ve spoken with experts and leaders in Washington and across the country. It’s become clear to me that we must take three steps.
First, we need a consistent nationwide approach to shutting down. Despite urging from public health experts, some states and counties haven’t shut down completely. In some states, beaches are still open; in others, restaurants still serve sit-down meals.
This is a recipe for disaster. Because people can travel freely across state lines, so can the virus. The country’s leaders need to be clear: Shutdown anywhere means shutdown everywhere. Until the case numbers start to go down across America—which could take 10 weeks or more—no one can continue business as usual or relax the shutdown. Any confusion about this point will only extend the economic pain, raise the odds that the virus will return, and cause more deaths.
Information from the UN System | United Nations
Second, the federal government needs to step up on testing. Far more tests should be made available. We should also aggregate the results so we can quickly identify potential volunteers for clinical trials and know with confidence when it’s time to return to normal. There are good examples to follow: New York state recently expanded its capacity to more than 25,000 tests per day.
There’s also been some progress on more efficient testing methods, such as the self-swab developed by the Seattle Coronavirus Assessment Network, which allows patients to take a sample themselves without possibly exposing a health worker. I hope this and other innovations in testing are scaled up across the country soon.Coronavirus: Here's how shelter in place, stay at home orders can ...
Even so, demand for tests will probably exceed the supply for some time, and right now, there’s little rhyme or reason to who gets the few that are available. As a result, we don’t have a good handle on how many cases there are or where the virus is likely headed next, and it will be hard to know if it rebounds later. And because of the backlog of samples, it can take seven days for results to arrive when we need them within 24 hours.
This is why the country needs clear priorities for who is tested. First on the list should be people in essential roles such as health-care workers and first responders followed by highly symptomatic people who are most at risk of becoming seriously ill and those who are likely to have been exposed.
FAQ: What does a stay at home order mean for NC? - News - The ...
The same goes for masks and ventilators. Forcing 50 governors to compete for lifesaving equipment—and hospitals to pay exorbitant prices for it—only makes matters worse.
Stay Home? Shelter-In-Place? Navigating Oregon's And Portland's ...
Portland via OPB
Finally, we need a data-based approach to developing treatments and a vaccine. Scientists are working full speed on both; in the meantime, leaders can help by not stoking rumors or panic buying. Long before the drug hydroxychloroquine was approved as an emergency treatment for COVID-19, people started hoarding it, making it hard to find for lupus patients who needed it to survive.
We should stick with the process that works: Run rapid trials involving various candidates and inform the public when the results are in. Once we have a safe and effective treatment, we’ll need to ensure that the first doses go to the people who need them most.Bill Gates calls Trump's freeze on WHO funding 'dangerous' and ...
To bring the disease to an end, we’ll need a safe and effective vaccine. If we do everything right, we could have one in less than 18 months—the fastest a vaccine has ever been developed. But creating a vaccine is only half the battle. To protect Americans and people around the world, we’ll need to manufacture billions of doses.
Without a vaccine, developing countries are at even greater risk than wealthy ones, because it’s even harder for them to do physical distancing and shutdowns. The further down the income ladder people live, the more important it is that they go to work every day just to feed their family.Gates Foundation boosts funding for coronavirus response to $250 ...
If they live in the poorest parts of sub-Saharan Africa or India, staying home simply isn’t an option. Even if they do stay home, they can’t just wall themselves off from their neighbors; in slums, the houses are packed together so closely that there’s no way to keep your distance. All the work that rich countries are doing now to develop vaccines will save lives in those places, too.
We can get a head start on manufacturing all of the doses we’ll need now by building the facilities where these vaccines will be made. Because many of the top candidates are made using unique equipment, we’ll have to build facilities for each of them, knowing that some won’t get used. Private companies can’t take that kind of risk, but the federal government can. It’s a great sign that the administration made deals this week with at least two companies to prepare for vaccine manufacturing. I hope more deals will follow.
In 2015, I urged world leaders in a TED talk to prepare for a pandemic the same way they prepare for war—by running simulations to find the cracks in the system. As we’ve seen this year, we have a long way to go. But I still believe that if we make the right decisions now, informed by science, data, and experience of medical professionals, we can save lives and get the country back to work.
A version of this post originally appeared on the website of the Washington Post.
31 questions and answers about COVID-19 | Bill Gates




TRANSCRIPT:

When I was a kid, the disaster we worried about most was a nuclear war. That's why we had a barrel like this down in our basement, filled with cans of food and water. When the nuclear attack came, we were supposed to go downstairs, hunker down, and eat out of that barrel.

Today the greatest risk of global catastrophe doesn't look like this. Instead, it looks like this. If anything kills over 10 million people in the next few decades, it's most likely to be a highly infectious virus rather than a war. Not missiles, but microbes. Now, part of the reason for this is that we've invested a huge amount in nuclear deterrents. But we've actually invested very little in a system to stop an epidemic. We're not ready for the next epidemic.

Let's look at Ebola. I'm sure all of you read about it in the newspaper, lots of tough challenges. I followed it carefully through the case analysis tools we use to track polio eradication. And as you look at what went on, the problem wasn't that there was a system that didn't work well enough, the problem was that we didn't have a system at all. In fact, there's some pretty obvious key missing pieces.

We didn't have a group of epidemiologists ready to go, who would have gone, seen what the disease was, seen how far it had spread. The case reports came in on paper. It was very delayed before they were put online and they were extremely inaccurate. We didn't have a medical team ready to go. We didn't have a way of preparing people. Now, Médecins Sans Frontières did a great job orchestrating volunteers. But even so, we were far slower than we should have been getting the thousands of workers into these countries. And a large epidemic would require us to have hundreds of thousands of workers. There was no one there to look at treatment approaches. No one to look at the diagnostics. No one to figure out what tools should be used. As an example, we could have taken the blood of survivors, processed it, and put that plasma back in people to protect them. But that was never tried.

So there was a lot that was missing. And these things are really a global failure. The WHO is funded to monitor epidemics, but not to do these things I talked about. Now, in the movies it's quite different. There's a group of handsome epidemiologists ready to go, they move in, they save the day, but that's just pure Hollywood.

The failure to prepare could allow the next epidemic to be dramatically more devastating than Ebola Let's look at the progression of Ebola over this year. About 10,000 people died, and nearly all were in the three West African countries. There's three reasons why it didn't spread more. The first is that there was a lot of heroic work by the health workers. They found the people and they prevented more infections. The second is the nature of the virus. Ebola does not spread through the air. And by the time you're contagious, most people are so sick that they're bedridden. Third, it didn't get into many urban areas. And that was just luck. If it had gotten into a lot more urban areas, the case numbers would have been much larger.

So next time, we might not be so lucky. You can have a virus where people feel well enough while they're infectious that they get on a plane or they go to a market. The source of the virus could be a natural epidemic like Ebola, or it could be bioterrorism. So there are things that would literally make things a thousand times worse.

In fact, let's look at a model of a virus spread through the air, like the Spanish Flu back in 1918. So here's what would happen: It would spread throughout the world very, very quickly. And you can see over 30 million people died from that epidemic. So this is a serious problem. We should be concerned.

But in fact, we can build a really good response system. We have the benefits of all the science and technology that we talk about here. We've got cell phones to get information from the public and get information out to them. We have satellite maps where we can see where people are and where they're moving. We have advances in biology that should dramatically change the turnaround time to look at a pathogen and be able to make drugs and vaccines that fit for that pathogen. So we can have tools, but those tools need to be put into an overall global health system. And we need preparedness.

The best lessons, I think, on how to get prepared are again, what we do for war. For soldiers, we have full-time, waiting to go. We have reserves that can scale us up to large numbers. NATO has a mobile unit that can deploy very rapidly. NATO does a lot of war games to check, are people well trained? Do they understand about fuel and logistics and the same radio frequencies? So they are absolutely ready to go. So those are the kinds of things we need to deal with an epidemic.

What are the key pieces? First, we need strong health systems in poor countries. That's where mothers can give birth safely, kids can get all their vaccines. But, also where we'll see the outbreak very early on. We need a medical reserve corps: lots of people who've got the training and background who are ready to go, with the expertise. And then we need to pair those medical people with the military. taking advantage of the military's ability to move fast, do logistics and secure areas. We need to do simulations, germ games, not war games, so that we see where the holes are. The last time a germ game was done in the United States was back in 2001, and it didn't go so well. So far the score is germs: 1, people: 0. Finally, we need lots of advanced R&D in areas of vaccines and diagnostics. There are some big breakthroughs, like the Adeno-associated virus, that could work very, very quickly.

Now I don't have an exact budget for what this would cost, but I'm quite sure it's very modest compared to the potential harm. The World Bank estimates that if we have a worldwide flu epidemic, global wealth will go down by over three trillion dollars and we'd have millions and millions of deaths. These investments offer significant benefits beyond just being ready for the epidemic. The primary healthcare, the R&D, those things would reduce global health equity and make the world more just as well as more safe.

So I think this should absolutely be a priority. There's no need to panic. We don't have to hoard cans of spaghetti or go down into the basement. But we need to get going, because time is not on our side.

In fact, if there's one positive thing that can come out of the Ebola epidemic, it's that it can serve as an early warning, a wake-up call, to get ready. If we start now, we can be ready for the next epidemic.

Thank you.
(Applause)

The next outbreak? We're not ready | Bill Gates - YouTube


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- Bloggery committed by chris tower - 2004.18 - 10:10

- Days ago = 1750 days ago

- New note - On 1807.06, I ceased daily transmission of my Hey Mom feature after three years of daily conversations. I plan to continue Hey Mom posts at least twice per week but will continue to post the days since ("Days Ago") count on my blog each day. The blog entry numbering in the title has changed to reflect total Sense of Doubt posts since I began the blog on 0705.04, which include Hey Mom posts, Daily Bowie posts, and Sense of Doubt posts. Hey Mom posts will still be numbered sequentially. New Hey Mom posts will use the same format as all the other Hey Mom posts; all other posts will feature this format seen here.

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